Platelet-rich plasma (PRP) is a concentrate of platelet-rich plasma protein derived from whole blood, centrifuged to removed red blood cells. It has a greater concentration of growth factors than whole blood and has been used to encourage a brisk healing response across several specialties, in particular dentistry, orthopedics and dermatology. As a concentrated source of blood plasma and autologous conditioned plasma, PRP contains several different growth factors platelet-derived growth factor (transforming growth factor beta, fibroblast growth factor, insulin-like growth factor 1, insulin-like growth factor 2, vascular endothelial growth factor, epidermal growth factor, Interleukin 8, keratinocyte growth factor, connective tissue growth factor) and other cytokines that can stimulate healing and growth.Main indications in dermatology for PRP are androgenic alopecia, wound healing, and skin rejuvenation. For the preparation of PRP, various protocols are used, with an underlying principle of concentrating platelets to 3–5 times physiological levels, then injecting this concentrate in the tissue where healing is desired. The efficacy of certain growth factors in healing various injuries and the concentrations of these growth factors found within PRP are the theoretical basis for the use of PRP in tissue repair. The platelets collected in PRP are activated by the addition of thrombin and calcium chloride, which induces the release of the mentioned factors from alpha granules. The growth factors and other cytokines present in PRP include:

PRP injection is a simple, cost-effective and feasible treatment option for :

  • Androgenetic alopecia(male patterned hair loss)
  • Female pattern hair loss
  • Acne scar reduction
  • Facial rejuvenation
  • Pigmentation reduction
  • Brightening
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